Sie befinden sich hier

Inhalt

MRT Bildgebung

Allgemein

Die Arbeitsgruppe Neurologische MRT-Bildgebung beschäftigt sich mit der Anwendung und Weiterentwicklung neuer MR Methoden bei unterschiedlichen Erkrankungen des zentralen Nervensystems mit den Schwerpunkten Multiple Sklerose und akuter Schlaganfall.

  • Diffusionsgewichtete Bildgebung
  • DTI / TBSS
  • Natrium (23Na) MRT
  • Arterial Spin Labelling (ASL) Perfusionsimaging
  • Gradienten-Echo Bildgebung (SWI, T2*)
  • Hirnatrophieanalysen
  • Voxel-Based-Morphometry (VBM)

Ausgewählte Publikationen

  • Eisele P, Szabo K, Griebe M, Rossmanith C, Förster A, Hennerici M, Gass A. Reduced diffusion in a subset of acute MS lesions: a serial multiparametric MRI study. AJNR Am J Neuroradiol. 2012 Aug;33(7):1369-73.
  • Eisele P, Szabo K, Griebe M, Wolf ME, Hennerici MG, Gass A. Cerebrospinal fluid pleocytosis in multiple sclerosis patients with lesions showing reduced diffusion. Mult Scler. 2014 Sep;20(10):1391-1395.
  • Eisele P, Griebe M, Szabo K, Wolf ME, Alonso A, Engelhardt B, Hennerici MG, Gass A. Investigation of Leptomeningeal Enhancement in MS - A post-contrast FLAIR MRI study. Neurology. 2015 Feb 24;84(8):770-775.
  • Alonso A*, Eisele P*, Ebert A, Griebe M, Engelhardt B, Szabo K, Hennerici MG, Gass A. Leptomeningeal contrast enhancement and blood-CSF barrier dysfunction in aseptic meningitis. Neurol Neuroimmunol Neuroinflamm December 2015 vol. 2 no. 6 e164.
  • Eisele P, Alonso A, Griebe M, Szabo K, Hennerici MG, Gass A. Investigation of cerebral microbleeds in multiple sclerosis as a potential marker of blood-brain-barrier dysfunction. Mult Scler Relat Disord. 2016 May;7:61-64.
  • Eisele P, Konstandin S, Griebe M, Szabo K, Wolf ME, Alonso A, Ebert A, Serwane J, Rossmanith C, Hennerici MG, Schad LR, Gass A. Heterogeneity of acute multiple sclerosis lesions on sodium (23Na) MRI. Mult Scler. 2016 Jul;22(8):1040-1047.
  • Eisele P, Alonso A, Szabo K, Ebert A, Ong M, Schoenberg SO, Gass A. Lack of increased signal intensity in the dentate nucleus after repeated administration of a macrocyclic contrast agent in multiple sclerosis: An observational study. Medicine (Baltimore) 2016;95:e4624.
  • Hoyer C, Eisele P*, Ebert AD, Schneider S, Gass A, Fatar M, Szabo K, Alonso A. Blood-CSF-barrier dysfunction is a marker for encephalitic involvement in patients with aseptic meningitis/meningoencephalitis. J Clin Virol. 2016 Oct 6;84:82-86.
  • Eisele P, Konstandin S, Szabo K, Ong M, Zöllner F, Schad LR, Schoenberg SO, Gass A. Sodium MRI of T1 high signal intensity in the dentate nucleus due to gadolinium deposition in multiple sclerosis. J Neuroimaging. 2017 Jul;27(4):372-375.
  • Popescu V, Agosta F, Hulst HE, Sluimer IC, Knol DL, Sormani MP, Enzinger C, Ropele S, Alonso J, Sastre-Garriga J, Rovira A, Montalban X, Bodini B, Ciccarelli O, Khaleeli Z, Chard DT, Matthews L, Palace J, Giorgio A, De Stefano N, Eisele P, Gass A, Polman CH, Uitdehaag BM, Messina MJ, Comi G, Filippi M, Barkhof F, Vrenken H; on behalf of the MAGNIMS Study Group. Brain atrophy and lesion load predict long term disability in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2013 Oct;84(10):1082-91.
  • Eisele P, Szabo K, Hornberger E, Griebe M, Hennerici MG, Kieseier BC, Gass A Presumptive Progressive Multifocal Leukoencephalopathy in Multiple Sclerosis after Natalizumab Therapy J Neuroimaging. 2014 Jul;24(4):425-8.
  • Eisele P, Griebe M, Szabo K, Wolf ME, Alonso A, Engelhardt B, Hennerici MG, Gass A. Investigation of Leptomeningeal Enhancement in MS - A post-contrast FLAIR MRI study. Neurology 2015;84:1–6.
  • Gass A, Rocca MA, Agosta F, Ciccarelli O, Chard D, Valsasina P, Brooks JC, Bischof A, Eisele P, Kappos L, Barkhof F, Filippi M, MAGNIMS Study Group Spinal cord pathology in MS visualized by MRI - new opportunities for monitoring disease progression Lancet Neurol. 2015 Apr;14(4):443-54.
  • Eisele P, Szabo K, Alonso A, Ong M, Platten M, Schoenberg SO, Gass A. Lack of T1 hyperintensity in the dentate nucleus after 15 administrations of a macrocyclic contrast agent in multiple sclerosis. J Neurol Neurosurg Psychiatry. 2018 Mar;89(3):324-326.
  • Eisele P, Szabo K, Ebert A, Brueck W, Platten M, Gass A. Spatiotemporal evolution of venous narrowing in acute MS lesions.Neurol Neuroimmunol Neuroinflamm. 2018 Jan 17;5(2):e440. doi: 10.1212/NXI.0000000000000440. eCollection 2018 Mar.

Kontextspalte

Achim Gass

Prof. Dr. med. Achim Gass

Oberarzt

Eisele, Philipp

PD Dr. med. Philipp Eisele

Oberarzt